Novel hypotensive imidazothiadiazolealkanecarboxamides

US4657905A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Axel Ingendoh · Velbert, DE
• Horst Meyer
• Bernward Garthoff · Hilden, DE

Key dates

• Filing date: Oct 21, 1985
• Grant date: Apr 14, 1987
• Expiry date: Oct 21, 2005

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P9/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Imidazothiadiazolealkenecarboxamides of the formula ##STR1## in which R.sup.1 is hydrogen, aryl, substituted aryl or a cyclic or aliphatic hydrocarbon radical which is optionally interrupted by O, S, N, N-alkyl, N-aryl or N-aralkyl and which is optionally substituted, PA1 R.sup.8 having the meaning indicated for R.sup.1, and PA1 X representing oxygen, sulphur or the radical NR.sup.9 R.sup.10, the other radical having various definitions, and acid addition salts thereof, exhibit hypotensive activity.