Nafazatrom as a lipoxygenase inhibitor

US4657924A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Mithat Mardin · Wuppertal, DE
• Wolf-Dieter Busse · Wuppertal, DE
• Friedrich Hoffmeister
• Friedel Seuter
• Elisabeth Perzborn · Wuppertal, DE
• Klaus Schlossmann · Wuppertal, DE
• Dieter Mayer · Werne, DE
• Volker-Bernd Fiedler · Leverkusen, DE

Key dates

• Filing date: Mar 25, 1985
• Grant date: Apr 14, 1987
• Expiry date: Mar 25, 2005

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K31/415
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A method of inhibiting lipoxygenase in a patient, for the prophylaxis and/or treatment of ischaemias and disorders in cardiac rhythm and of rheumatic, allergic and asthmatic diseases, oedemas, pulmonary embolisms, pulmonary hypertension, oxygen intoxications and ulcerations which comprises administering to such patient an effective amount of nafazatrom.