2-(4,5-Dihydro-1H-imidazol-2-yl)-2,3-dihydroindole derivatives and their application as .alpha..sub.2 receptor antagonist or .alpha..sub.1 receptor agonists
US4659731A · kind A · utility
11Cited by
1References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 5, 1986 |
| Grant date | Apr 21, 1987 |
| Priority date | — |
| Expiry date | Feb 5, 2006 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D209/42
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Derivatives of formula (I) ##STR1## in which X denotes a hydrogen or halogen atom, an alkoxy radical, an alkyl radical or an allyloxy radical, and R denotes a linear or branched alkyl radical, a cycloalkylalkyl radical, an alkenyl radical, an arylalkyl radical which can bear one or more substituents chosen from halogen atoms and methyl, methoxy and methylenedioxy radicals, or alternatively an optionally substituted phenyl radical, as well as the addition salts thereof with pharmaceutically acceptable acids produce an .alpha..sub.2 -receptor antagonist effect.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.