Glass-surface microcarrier for anchorage-dependent cell cultivation
US4661407A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Oct 24, 1985 |
| Grant date | Apr 28, 1987 |
| Priority date | — |
| Expiry date | Oct 24, 2005 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T428/2998
- WIPO fieldSurface technology, coating
- WIPO sectorChemistry
Abstract
A chemical vapor deposition process for making glass-surfaced microcarriers, and the resulting product, in which hollow spherical micro-sized shells of glass or ceramic composition replaced within a fluidized bed coater, and separate preheated reaction gasses are directed into the coater bed. The shell precursors have a preferred starting density of not more than the predetermined desired final density in the range of 1.01 to 1.2 g/cc, and have a diameter in the range of 5 to 500 .mu.m, preferably 105 to 150 .mu.m. The thickness of the silicate glass coating is preferably in the range of 11 to 16 .mu.m. An alternative embodiment employs solid precursor beads of polyphenylene oxide.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.