Homogeneous immunoassays employing double antibody conjugates comprising anti-idiotype antibody
US4661444A · kind A · utility
37Cited by
1References
13Claims
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Key dates
| Filing date | Mar 29, 1984 |
| Grant date | Apr 28, 1987 |
| Priority date | — |
| Expiry date | Mar 29, 2004 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S436/80
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Homogeneous immunoassays employing double ligand binding conjugates comprising an anti-idiotype binding partner. The anti-idiotype binding partner competes with ligand for an insolubilized ligand specific binding partner. Inhibition of binding of the conjugate to the insolubilized binding partner due to ligand binding permits the second binding partner in the conjugate to bind with insolubilized label means. Thus, detection of label is inversely related to the presence of ligand in the sample.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.