Formamido oxacephems
US4661480A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Jan 19, 1984 |
| Grant date | Apr 28, 1987 |
| Priority date | — |
| Expiry date | Jan 19, 2004 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D505/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A compound of formula (I) or a pharmaceutically acceptable salt or in vivo hydrolyzable ester thereof: ##STR1## R is phenyl, substituted phenyl, C.sub.3-6 cycloalkyl cyclohexenyl, cyclohexadienyl, or a 5- or 6-membered heterocyclic ring containing up to three hetero-atoms slected from oxygen, sulphur or nitrogen, optionally substituted with hydroxy, amino, halogen, substituted amino or C.sub.1-6 alkoxy; Q represents acetoxy, carbamoyloxy, heterocyclylthio group, or a nitrogen containing heterocyclic group bonded via nitrogen; R.sup.1 is hydrogen or a C.sub.1-6 alkyl group and R.sup.2 is an optionally substituted 5- or 6-membered heterocyclic group containing one or two heteroatoms; or R.sup.1 and R.sup.2 together with the nitrogen atom to which they are attached form an optionally substituted five- or six-membered heterocyclic group containing one or two nitrogen heteroatoms; a process for the preparation of such compounds and pharmaceutical compositions comprising them.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.