Patent · US Expired

Process for reducing reflex tachycardia in the treatment of hypertension employing a combination of a diazacyclopentene derivative and a pyridazinone derivative

US4661487A · kind A · utility

0Cited by

2References

2Claims

0Family size

Assignee

A NATTERMANN & CIE GMBH · DE

Inventors

Jurgen Biedermann · Pulheim, DE
Harald Borbe · Mainz, DE
Erich Graf · Kerpen, DE
Gerd Hilboll · Pulheim, DE
Gerrit Prop · Pulheim, DE

Key dates

Filing date	Feb 26, 1985
Grant date	Apr 28, 1987
Priority date	—
Expiry date	Feb 26, 2005

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P9/12
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to a new process for the treatment of hypertension and thromboembolic diseases in humans by simultaneous administration of (.+-.)- or (-)-2-[1-(2,6-dichlorophenoxy)-ethyl]-1,3-diazacyclopent-2-ene hydrochloride on the one side, and 4,5-dihydro-6-[4-(1-imidazolyl)-phenyl]-5-methyl-3(2H)-pyridazinone or 4,5-dihydro-6-[4-(1-imidazolyl)-thien-2-yl]-5-methyl-3(2H)-pyridazinone, on the other side, as the active substances.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.