Monoclonal anti-idiotype antibodies

US4661586A · kind A · utility

Assignee

• The Board of Trustees of the Leland Stanford Junior University · US

Inventors

• Ronald Levy · Palo Alto, US
• Jeanette Dilley · Bishop, US
• David MALONEY · Point of Rocks, US
• Richard A. Miller · Kingsport, US

Key dates

• Filing date: Dec 2, 1983
• Grant date: Apr 28, 1987
• Expiry date: Dec 2, 2003

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S530/865
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Monoclonal anti-idiotype antibodies against cell surface Ig of human B-cell tumors, labeled conjugates of such antibodies, immunotherapeutic compositions containing such antibodies, and a process for making such antibodies. The nodular lymphoma of a patient treated with a monoclonal anti-idiotpye antibody against the cell surface IgM of the patient's tumor went into complete remission.