Aralykyl (arylethynyl)aralkyl amines and their use as vasodilators and antihypertensives
US4661635A · kind A · utility
15Cited by
1References
32Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Oct 29, 1984 |
| Grant date | Apr 28, 1987 |
| Priority date | — |
| Expiry date | Oct 29, 2004 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F1/08
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Acetylenes of the formula (I): ##STR1## wherein Y, m, R.sup.1, R.sup.2 q, Alk, R.sup.3, n and R.sup.4 are as defined herein and Ar.sup.1 and Ar.sup.2 are aromatic, including the salts and ammonium derivatives of formula (I), in treating angina, hypertension and cardiac arrhythmias. Pharmaceutical compositions, methods of use and synthesis and novel intermediates are also part of the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.