Isotopic generator for bismuth-212 and lead-212 from radium
US4663129A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jan 30, 1985 |
| Grant date | May 5, 1987 |
| Priority date | — |
| Expiry date | Jan 30, 2005 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG21G4/08
- WIPO fieldEngines, pumps, turbines
- WIPO sectorMechanical engineering
Abstract
A method and apparatus for providing radionuclides of bismuth-212 and lead-212. Thorium-228 and carrier solution starting material is input to a radiologically contained portion of an isotopic generator system, and radium-224 is separated from thorium-228 which is retained by a strongly basic anion exchange column. The separated radium-224 is transferred to an accessible, strongly acidic cationic exchange column. The cationic column retains the radium-224, and natural radioactive decay generates bismuth-212 and lead-212. The cationic exchange column can also be separated from the contained portion of the system and utilized without the extraordinary safety measures necessary in the contained portion. Furthermore, the cationic exchange column provides over a relatively long time period the short lived lead-212 and bismuth-212 radionuclides which are useful for a variety of medical therapies.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.