Derivatives of muramyl-peptides and of steroids having macrophage-activating properties
US4663311A · kind A · utility
5Cited by
0References
13Claims
0Family size
Inventors
Key dates
| Filing date | Aug 16, 1984 |
| Grant date | May 5, 1987 |
| Priority date | — |
| Expiry date | Aug 16, 2004 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P37/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to compounds resulting from a covalent conjugation of the muramyl-peptide and the steroid particularly with membranal tropism, such as cholesterol, a precursor of its biosynthesis, or a steroid which is derived therefrom including a hydroxyl or amine group. Suspensions of liposomes including these compounds have macrophage activating properties.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.