Tetrazole derivatives, anti-ulcer composition containing the same and method for treating ulcers
US4663323A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | May 11, 1984 |
| Grant date | May 5, 1987 |
| Priority date | — |
| Expiry date | May 11, 2004 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D257/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Tetrazole derivatives of the formula: ##STR1## wherein R.sup.1 is an optional defined substituent; A is sulfur or a lower alkylene-thio, l is 0 or 1; B is a lower alkylene; R.sup.2 is hydroxy, a lower alkoxy, or a group: ##STR2## wherein R.sup.3 and R.sup.4 are optional defined substituents, or the R.sup.3 and R.sup.4 may combine together with the nitrogen atom to which they are joined to form a defined heterocyclic group, and a pharmaceutically acceptable salt thereof, which have prophylactic or therapeutic activities against peptic and/or duodenal ulcers and also anti-inflammatory activity and are useful as an anti-ulcer or anti-inflammatory drug; processes for the preparation of the tetrazole derivatives; and pharmaceutical composition containing said tetrazole derivatives.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.