Substituted naphthalenyloxy-1,2-diaminocyclohexyl amide compounds
US4663343A · kind A · utility
64Cited by
3References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 19, 1985 |
| Grant date | May 5, 1987 |
| Priority date | — |
| Expiry date | Jul 19, 2005 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D295/135
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Substituted naphthalenyloxy- or naphthalenylthiooxyamides of trans-1,2-diaminocyclohexanes possess selective kappa opioid receptor site binding activity and are thus useful as analgesic or diuretic agents. Methods of preparing the compounds, pharmaceutical compositions, and a method for their use as analgesic agents are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.