1-fluoro, 4-fluoro, and 1,4-difluoro-2'-halo anthracycline antibiotics
US4663445A · kind A · utility
1Cited by
3References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 20, 1985 |
| Grant date | May 5, 1987 |
| Priority date | — |
| Expiry date | Mar 20, 2005 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H15/252
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Anthracycline antibiotics represented by the formula (I) ##STR1## wherein R is hydrogen or hydroxyl, one of X and Y is fluorine and the other is hydrogen or both X and Y are fluorine, and S is a 2-halo sugar moiety; pharmaceutical preparations containing the same; and a method for inhibiting the growth of mammalian tumors are disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.