Patent · US Expired

Process for the synthesis of penems and penams

US4663451A · kind A · utility

1Cited by
2References
9Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 29, 1984
Grant dateMay 5, 1987
Priority date
Expiry dateAug 29, 2004

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P31/04
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Described is a novel process for the preparation of penams and penems useful as antibacterial agents, which comprises the reaction of an appropriate 4-substituted-azetidin-2-one with a base, followed by reaction of the thereby formed penam compound with an oxidating agent and a organic or inorganic base. Also described are novel penam compounds useful as antibacterials which are prepared by the described process.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.