Process for purifying 4-hydroxyacetophenone
US4663485A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 22, 1986 |
| Grant date | May 5, 1987 |
| Priority date | — |
| Expiry date | Jul 22, 2006 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C45/83
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process is provided for the distillation of a composition containing 4-hydroxyacetophenone and hydrogen fluoride in the presence of an alkane assisting solvent having from 4 to 16 carbon atoms e.g. n-hexane or n-octane. The process is carried out to obtain an overhead vapor containing alkane solvent and most of the hydrogen fluoride in the feed, and a liquid residue containing most of the 4-hydroxyacetophenone in the feed. The overhead vapor is condensed to form two immiscible phases, one containing a preponderance of hydrogen fluoride and the other a preponderance of alkane solvent, with the latter phase being returned to the distillation as reflux. The liquid residue also separates into two immiscible layers, one containing most of the 4-hydroxyacetophenone in the feed which is recovered and the other a preponderance of alkane solvent.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.