Patent · US Expired

3-thiazolomethyl cephalosporins as antibiotics

US4665066A · kind A · utility

4Cited by
7References
6Claims
0Family size

Assignee

Inventor

Key dates

Filing dateDec 24, 1984
Grant dateMay 12, 1987
Priority date
Expiry dateDec 24, 2004

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D463/22
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

7.beta.-[2-(2-Aminothiazol(oxazol)-4-yl)-2-oximinoacetamido]-3-(thiazolium or substituted thiazolium-3-yl)methyl-3-cephem-4-carboxylates and the correspondingly substituted 1-oxadethia and 1-carbadethia 3-cephem compounds are potent antibacterials useful in a therapeutic method for treating bacterial diseases. Also provided are pharmaceutical formulations of these thiazolium-substituted compounds and intermediates useful in the preparation thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.