Patent · US Expired

Radioactive diagnostic agent

US4666697A · kind A · utility

10Cited by
4References
24Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 5, 1983
Grant dateMay 19, 1987
Priority date
Expiry dateDec 5, 2003

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K2123/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A radioactive diagnostic agent which comprises (1) a unit of a polyformyl compound having at least three formyl groups per molecule, (2) at least two units of an amino group-containing chelating compound bonded to the polyformyl compound a methyleneimine linkage (--CH.dbd.N--) or a methyleneamine linkage (--.sub.2 NH--) formed by the condensation between the formyl group in the polyformyl compound and the amino group in the chelating compound, optionally followed by reduction, (3) at least one unit of an amino group-containing physiologically active substance bonded to the polyformyl compound by a methyleneimine linkage or a methyleneamine linkage formed by the condensation between the formyl group in the polyformyl compound and the amino group in the physiologically active substance, optionally followed by reduction, and (4) at least two radioactive metallic elements of which each is bonded to the chelating compound through a chelating bond.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.