Patent · US Expired

Polymers for the purification of acarbose

US4666776A · kind A · utility

4Cited by

3References

6Claims

0Family size

Assignee

BAYER HEALTHCARE LLC · DE

Inventors

Peter M. Lange · Leverkusen, DE
Erich Rauenbusch · Wuppertal, DE

Key dates

Filing date	Oct 10, 1985
Grant date	May 19, 1987
Priority date	—
Expiry date	Oct 10, 2005

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10T428/2982
WIPO fieldChemical engineering
WIPO sectorChemistry

Abstract

In the purification of acarbose by contacting an acarbose-containing solution with a cation exchanger to adsorb the acarbose, eluting the ion exchanger and collecting an eluate fraction enriched in purified acarbose, the improvement wherein the cation exchanger is a polymer obtained by polymerizing an aromatic compound possessing at least one vinyl group and at least one hydrophilic monomer in the presence of a solvent for the monomer which is a precipitant for the crosslinked polymer formed, isolating the resistant polymer, and sulphonating the polymer in the presence of a swelling agent for the polymer. The invention gives shapr separation and other processing advantages.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.