Patent · US Expired

DNA sequences, recombinant DNA molecules and processes for producing the A and B subunits of cholera toxin and preparations containing so-obtained subunit or subunits

US4666837A · kind A · utility

33Cited by
5References
26Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 24, 1982
Grant dateMay 19, 1987
Priority date
Expiry dateMay 24, 2002

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S435/909
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

DNA sequences and recombinant DNA molecules comprising at least a portion coding for all or part of subunits A and/or B of cholera toxin are prepared by enzymatic digestion of DNA of V. cholerae strains, isolating specific fragments and inserting them in appropriate vectors and subunits A and/or B of cholera toxin are prepared by culture of microorganisms containing said modified vectors.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.