Process for the preparation of L-.alpha.-aminoacids
US4666840A · kind A · utility
3Cited by
9References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 31, 1985 |
| Grant date | May 19, 1987 |
| Priority date | — |
| Expiry date | Jan 31, 2005 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P17/10
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The process of the invention is useful for the preparation of L-.alpha.-aminoacids and is based on the use of an N-carbamyl-.alpha.-aminoacid compound which is contacted with a E.C.3.5.2.2, a dihydropyrimidine hydrolase, enzyme to form a D-hydantoin. The D-hydantoin is hydrolyzed and racemized to form the D-N-carbamyl-.alpha.-aminoacid and the L-N-carbonyl-.alpha.-aminoacid. The L-N-carbamyl-.alpha.-aminoacid is thereafter transformed into the corresponding L-.alpha.-aminoacid.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.