Tetrahydropyridazinone derivatives, processes for their preparation and their use

US4666902A · kind A · utility

Assignee

• Cassella Aktiengesellschaft · DE

Inventors

• Gerhard Zoller · Blankenloch, DE
• Rudi Beyerle · Frankfurt, DE
• Melitta Just · Langen, DE
• Piero Martorana · Bad Homburg vor der Höhe, DE
• Helmut Bohn · Schöneck, DE
• Rolf-Eberhard Nitz · Frankfurt am Main, DE

Key dates

• Filing date: Jun 8, 1984
• Grant date: May 19, 1987
• Expiry date: Jun 8, 2004

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D413/12
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Tetrahydropyridazinones of the formula I ##STR1## wherein R denotes an optionally substituted carbocyclic or heterocyclic radical, R.sup.1 denotes hydrogen; alkyl; aralkyl, which is optionally substituted in the aryl part; or acyl, and R.sup.2 denotes hydrogen; alkyl, which can optionally be substituted; or optionally substituted phenyl; and their acid addition compounds, if these can be prepared. The tetrahydropyridazinone derivatives of the formula I according to the invention and their physiologically acceptable salts exhibit useful pharmacological actions.