Pyrazole derivatives, processes for their preparation and pharmaceutical preparations containing these compounds

US4666921A · kind A · utility

Assignee

• Ludwig Heumann & Co. GmbH · DE

Inventors

• Rolf Herter · Schwabach, DE
• Helmut Schickaneder · Eckental, DE
• Peter Morsdorf · Langenzenn, DE
• Stefan Postius · Konstanz, DE
• Istvan Szelenyi · Arnstorf, DE
• Kurt H. Ahrens · Nürnberg, DE

Key dates

• Filing date: Oct 15, 1985
• Grant date: May 19, 1987
• Expiry date: Oct 15, 2005

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D231/52
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Special pyrazole derivatives corresponding to the general formula I which have a highly selective action on histamine-H.sub.2 receptors are described. Compared with other drugs known to be effective in their action on histamine-H.sub.2 receptors, these compounds have improved pharmacological properties. A method of preparation of these compounds is also described.