Method of causing the reduction of physiological and/or subjective reactivity to stress in humans being subjected to stress conditions

US4670264A · kind A · utility

Assignees

• International Flavors & Fragrances Inc. · US
• Yale University · US

Inventors

• Craig B. Warren · Rumson, US
• Marina A. Munteanu · New York, US
• Gary E. Schwartz · Guilford, US
• Carlos Benaim · Mount Kisco, US
• Henry G. Walter, Jr. · Mill Neck, US
• Ronald S. Leight · Aberdeen, US
• Donald A. Withycombe · Lincroft, US
• Braja D. Mookherjee · Holmdel, US
• Robert W. Trenkle · Point Pleasant, US

Key dates

• Filing date: Nov 21, 1985
• Grant date: Jun 2, 1987
• Expiry date: Nov 21, 2005

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P25/20
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Described is a method for reducing physiological and/or subjective reactivity to stress in humans being subjected to stress conditions. The method consists of administering to such humans an effective amount of a physiological and/or subjective stress reactivity-reducing substance selected from the group consisting of: PA1 (i) Nutmeg Oil; PA1 (ii) Mace Extract; PA1 (iii) Neroli Oil; PA1 (iv) Valerian Oil; PA1 (v) Myristicin; PA1 (vi) Isoelemicin; and PA1 (vii) Elemicin. Administration is through inhalation or transdermally using one or more of the above ingredients alone or in a suitable composition such as ethanol and/or a perfume composition, cologne or perfumed article (e.g., air freshener or deodorant stick). Also described is a method for detecting the reduction of physiological and/or subjective reactivity to stress in a human.