Epoxy steroids
US4670551A · kind A · utility
1Cited by
2References
5Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jun 13, 1985 |
| Grant date | Jun 2, 1987 |
| Priority date | — |
| Expiry date | Jun 13, 2005 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07J71/0015
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
7.alpha.-acylthio-9.alpha.,11.alpha.-epoxy-20-spirox-4-ene-3,21-diones of the formula I ##STR1## in which R represents lower alkanoyl and --A--A-- represents an ethylene or cyclopropylene group, have a high aldosterone-antagonistic activity without significant sexually-specific side-effects and can be used as potassium-protecting diuretics in the treatment of various forms of hyperaldosteronism. The compounds can be obtained by conventional processes of steroid chemistry.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.