2-oxo-1-(aminocarbonylaminosulfonyl-aminocarbonyl)azetidines
US4670553A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Nov 26, 1982 |
| Grant date | Jun 2, 1987 |
| Priority date | — |
| Expiry date | Nov 26, 2002 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D417/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Antibacterial activity is exhibited by compounds having the formula ##STR1## and salts thereof, wherein R.sub.1 is acyl; PA1 R.sub.2 is hydrogen or methoxy; PA1 R.sub.3 and R.sub.4 are the same or different and each is hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, aryl or a 5,6 or 7-membered heterocycle or one of R.sub.3 and R.sub.4 is hydrogen and the other is azido, halomethyl, dihalomethyl, trihalomethyl, alkoxycarbonyl, 2-phenylethenyl, 2-phenylethynyl, carboxyl, ##STR2## X.sub.1 is azido, amino, hydroxy, alkanoylamino, alkylsulfonyloxy, arylsulfonyloxy, aryl, cyano, --S--X.sub.2 or --O--X.sub.2 ; PA1 X.sub.2 is alkyl, substituted alkyl, aryl, arylalkyl, alkanoyl, substituted alkanoyl, arylcarbonyl or heteroarylcarbonyl; PA1 one of X.sub.3 and X.sub.4 is hydrogen and the other is hydrogen or alkyl, or X.sub.3 and X.sub.4 when taken together with the carbon atom to which they are attached from a cycloalkyl group; PA1 X.sub.5 is formyl, alkanoyl, arylcarbonyl, arylalkylcarbonyl, carboxyl, alkoxycarbonyl, aminocarbonyl, (substituted amino)carbonyl, or cyano; PA1 A is --CH.dbd.CH--, --CH.sub.2 --CH.dbd.CH--, --(CH.sub.2)--.sub.m, --(CH.sub.2).sub.m' --O--, --(CH.sub.2).sub.m' --NH…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.