Alpha-functionalized derivatives and labeled conjugates of procainamide and NAPA
US4673763A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 18, 1985 |
| Grant date | Jun 16, 1987 |
| Priority date | — |
| Expiry date | Mar 18, 2005 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/9453
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Procainamide and N-acetylprocainamide (NAPA) immunogens, antibodies prepared therefrom, labeled conjugates, synthetic intermediates, and the use of such antibodies and labeled conjugates in immunoassays for determining the respective drugs. The immunogens comprise the drugs coupled at the .alpha.-position of the amide side chain to an immunogenic carrier material. The labeled conjugates and synthetic intermediates similarly are .alpha.-position derivatives of the drugs or precursors thereof. The antibodies and labeled conjugates are particularly useful in homogeneous nonradioisotopic immunoassays for measuring the respective drugs in biological fluids such as serum.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.