Patent · US Expired

Synthesis of indolizidines related to the carditonic pumiliotoxin a alkaloids

US4675325A · kind A · utility

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18Claims
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Assignee

Inventors

Key dates

Filing dateJun 21, 1984
Grant dateJun 23, 1987
Priority date
Expiry dateJun 21, 2004

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K31/445
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A method of making dendrobatid alkaloids with the formula ##STR1## in which A is either CH.sub.3 or H, and n is an integer from 1-9, and R is CH.sub.2 OH, CHO, ##STR2## and R.sub.1 and R.sub.2 are alkyl groups; and the use of such alkaloids to treat cardiovascular illness.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.