Fractionation/purification of plasma by ion exchange chromatography
US4675384A · kind A · utility
46Cited by
8References
25Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Apr 2, 1984 |
| Grant date | Jun 23, 1987 |
| Priority date | — |
| Expiry date | Apr 2, 2004 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The plasma proteins contained in a plasma solution thereof are chromatographically fractioned, e.g., to obtain a high purity therapeutic grade albumin product, by successively contacting said plasma solution with at least one anion exchanger and at least one cation exchanger in fixed bed chromatography columns, the contact and exchange medium of chromatography therein also comprising a plurality of at least partially hydrophobic support particulates and a plurality of hydrophilic ion exchanger support particulates.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.