Process for the preparation of benzimidazole-thiol
US4675413A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 19, 1985 |
| Grant date | Jun 23, 1987 |
| Priority date | — |
| Expiry date | Dec 19, 2005 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D235/32
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A new process is disclosed for preparing a compound of the formula (I) ##STR1## wherein R is C.sub.1 to C.sub.5 alkyl; which comprises reducing a compound of the formula (II) ##STR2## or salt thereof wherein A is --SO.sub.2 X, --SOH, --SOA.sup.1, or --SA.sup.1 group, PA0 X is chlorine or hydrogen; and PA0 A.sup.1 is a group of the Formula ##STR3## with the aid of aluminum activated with a catalytic amount of a metal and/or metal salt in a mixture of water, a mineral acid, and an aliphatic carboxylic acid having 1 to 3 carbon atoms at a temperature of 0.degree. to 100.degree. C., thereafter, optionally, the product is recovered from an acid medium at a pH range of 2 to 3 in crystalline form.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.