Conjugates of anticoagulant and protein
US4678671A · kind A · utility
30Cited by
8References
2Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 9, 1986 |
| Grant date | Jul 7, 1987 |
| Priority date | — |
| Expiry date | Sep 9, 2006 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T428/2933
- WIPO fieldMacromolecular chemistry, polymers
- WIPO sectorChemistry
Abstract
Conjugates are provided which are covalently bonded conjugates of an anticoagulant and protein that are prepared in the presence of a coupling agent that forms amide linkages between the anticoagulant and the protein. Such amide linking coupling agents exclude highly toxic coupling agents such as CNBr. These conjugates are useful for enhancing the blood compatibility of certain surfaces of a prosthetic device, a surgical apparatus, or an extra-corporeal medical device.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.