3-substituted-aminomethyl cephalosporin derivatives
US4678781A · kind A · utility
17Cited by
2References
11Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jun 4, 1984 |
| Grant date | Jul 7, 1987 |
| Priority date | — |
| Expiry date | Jun 4, 2004 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P31/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A cephalosporin derivative of the formula I: ##STR1## in which X is S, O, CH.sub.2 or SO, R1 is (optionally-substituted)imidazol-2-yl or one of the C-7 acyl groups known in the cephalosporin art, R2 is hydrogen or methoxy, R3 is carboxy or a biodegradable ester thereof and --R4 is of the formula XII, XIII or XIV: ##STR2## in which R32-R40 inclusive are as defined in the specification; and the salts thereof. Pharmaceutical compositions, methods of manufacture and intermediates are also described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.