Quaternary 3,4-dihydro-isoquinolinium salts

US4678792A · kind A · utility

Assignee

• Dr. Karl Thomae GmbH · DE

Inventors

• Josef Nickl
• Erich Muller · Zell am Harmersbach, DE
• Benthold Narr · Biberach, DE
• Helmut Ballhause · Biberach, DE
• Walter Haarmann

Key dates

• Filing date: Feb 28, 1985
• Grant date: Jul 7, 1987
• Expiry date: Feb 28, 2005

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D217/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

This invention relates to a compound of formula (I) ##STR1## wherein R.sub.1 and R.sub.2 are each independently hydrogen, C.sub.1 -C.sub.3 alkyl or C.sub.1 -C.sub.3 alkoxy; and R.sub.3 is a C.sub.7 -C.sub.9 aralkyl, the phenyl nucleus of which can be mono-, di-, or trisubstituted by halogen, C.sub.1 -C.sub.3 alkyl or C.sub.1 -C.sub.3 alkoxy, and nontoxic, pharmaceutically acceptable salts thereof. The compounds have useful antithrombic properties.