Immobilization of cells and enzymes

US4681843A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Peter Egerer · Wuppertal, DE
• Wulf Crueger · Erkrath, DE
• Christian Golker · Wuppertal, DE

Key dates

• Filing date: Feb 22, 1985
• Grant date: Jul 21, 1987
• Expiry date: Feb 22, 2005

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12P19/24
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

When immobilizing cells and/or enzymes by contact with tannin, epihalohydrin/polyamine copolymer and glutaraldehyde, immobilizing is carried out in the presence of a primary amine. The primary amine is preferably sulfuric acid mono-(2-aminoethyl)-ester, 2-aminoethanol, glycine or tris-(hydroxymethyl)-amino methane. The resulting immobilized cells and/or enzymes retain a higher proportion of their original activity.