Patent · US Expired

Erythromycin A 11,12-carbonate and method of use

US4681872A · kind A · utility

3Cited by
3References
4Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 12, 1985
Grant dateJul 21, 1987
Priority date
Expiry dateNov 12, 2005

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07H17/08
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

An erythromycin A derivative with high antimicrobial activity and improved pharmacokinetics is disclosed. 4"-Deoxyerythromycin A 11,12-carbonate and derivatives show superior in vitro and in vivo antimicrobial activity compared to erythromycin A, and when administered to animals has a serum half-life much prolonged over that of erythromycin A.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.