Preparation of nicotinamide

US4681946A · kind A · utility

Assignee

• BASF SE

Inventors

• Karl Baur · Baierbrunn, DE
• Volker Diehl · Ellerstadt, DE
• Peter Stops · Altrip, DE
• Hans Hellbach · Bischofswerda, DE
• Erwin Brunner · Meiningen, DE

Key dates

• Filing date: Nov 14, 1985
• Grant date: Jul 21, 1987
• Expiry date: Nov 14, 2005

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D213/81
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A process for the preparation of nicotinamide by amidation of a nicotinic acid/nicotinamide melt, vacuum distillation of the amidation mixture, removal of the nicotinamide as the bottom product and recycling of the top product, depleted with respect to nicotinamide, into the amidation stage together with addition of fresh amounts of nicotinic acid.