Use of tumor necrosis factor as a weight regulator

US4684623A · kind A · utility

Assignees

• Cetus Corporation · US
• The Board of Trustees of the Leland Stanford Junior University · US

Inventors

• James W. Larrick · Sunnyvale, US
• Gordon Ringold · Palo Alto, US
• David F. Mark · Plainsboro, US
• Leo S. Lin · Walnut Creek, US
• Frank Torti · Palo Alto, US

Key dates

• Filing date: Nov 26, 1985
• Grant date: Aug 4, 1987
• Expiry date: Nov 26, 2005

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S930/144
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A method for controlling weight by suppressing the normal metabolism of adipose tissue is disclosed. Administration of tumor necrosis factor (TNF) or a pharmaceutical composition containing it results in suppression of anabolism of adipose cells.