Formulation with special 1,2-diacylglycero-3-phosphocholines for the treatment of gastrointestinal disorders

US4684632A · kind A · utility

Assignee

• A NATTERMANN & CIE GMBH · DE

Inventors

• Volker Schulz · Cologne, DE
• Sigurd Leyck · Pulheim, DE
• Manfred Durr · Bad Sobernheim, DE
• Miklos Ghyczy · Cologne, DE
• Armin Wendel · Cologne, DE
• Jorg Hager · Cologne, DE

Key dates

• Filing date: Dec 21, 1984
• Grant date: Aug 4, 1987
• Expiry date: Dec 21, 2004

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07F9/10
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Pharmaceutical formulations for the treatment of gastrointestinal disorders, which contain as the active component an effective gastrointestinal disorder alleviating amount of a 1,2-diacylglycero-3-phosphocholine in which 75-86% by weight of the acyl radicals are unsaturated fatty acid radicals having a chain length of 16, 18 or 20 carbon atoms. The mixtures of fatty acid radicals in the acyl groups in the 1- and 2-positions preferably have different compositions. The formulations can also contain other active compounds, in particular those which display injurious gastrointestinal side effects.