Solubilizing biologically active compounds with reactive hydrogen atoms

US4684728A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Edgar Mohring · Bensberg, DE
• Hanns P. Muller · Leverkusen, DE
• Peter Roessler · Bensberg, DE
• Kuno Wagner · Leverkusen, DE
• Helmut Tietz · Leverkusen, DE

Key dates

• Filing date: Dec 28, 1979
• Grant date: Aug 4, 1987
• Expiry date: Dec 28, 1999

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C08G65/329
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A biologically active compound can be solubilized by reaction in different sequences to form a derivative carrying the active moiety, a linking group such as an optionally substituted diisocyanate radical, a polyether moiety such as a polyoxyethylene radical, and a terminal group such as a butyl radical, e.g. ##STR1## n=1 to 400. The active materials can be agricultural chemicals, pharmaceuticals, and the like.