Erythromycin A 11,12-carbonates and method of use
US4686207A · kind A · utility
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2References
3Claims
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Assignee
Inventors
Key dates
| Filing date | Nov 12, 1985 |
| Grant date | Aug 11, 1987 |
| Priority date | — |
| Expiry date | Nov 12, 2005 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H17/08
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Disclosed herein are erythromycin derivatives of the formula ##STR1## wherein R.sub.1 is lower alkyl, aryl, alkene, aryl halide, alkylamino, hydroxyalkyl and furanyl, and pharmaceutically acceptable salts thereof. These compounds have improved oral absorption, reduced effects on gastrointestinal motility, increased acid stability and longer serum half-lives.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.