Patent · US Expired

Medical composition for external application

US4686211A · kind A · utility

52Cited by
0References
11Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 20, 1985
Grant dateAug 11, 1987
Priority date
Expiry dateSep 20, 2005

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07F9/091
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A medical composition for external application comprises a dialkyl phosphate represented by the formula: ##STR1## wherein R.sub.1 and R.sub.2 independently represent a hydrocarbon group having from 6 to 24 carbon atoms, R.sub.3 and R.sub.4 independently represent hydrocarbon group having from 2 to 6 carbon atoms, m and n independently represent a value of from 0 to 20, and x represents a hydrogen atom or a salt of an alkali metal and the like. In the presence of the dialkyl phosphate, percutaneous intake of medically active ingredients is highly enhanced. Examples of the medically active ingredients directed to in the invention include antiinflammatory agents such as ethyl aminobenzoate; adrenocortical hormones such as hydrocortisone; etc. The inventive composition is highly safe without giving any stimulation to the skin.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.