Preparation of 2-aminopyrazines and pyrazines

US4687848A · kind A · utility

Assignee

• BASF SE

Inventors

• Fritz Brunnmueller · Schifferstadt, DE
• Michael Kroener · Mannheim, DE

Key dates

• Filing date: Jun 3, 1985
• Grant date: Aug 18, 1987
• Expiry date: Jun 3, 2005

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D241/20
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Novel 2-aminopyrazines and processes for the preparation of 2-aminopyrazines and pyrazines by reaction of an .alpha.-iminodiacetonitrile (a) with a hydrogen halide or (b) with an alcohol or a thioalcohol and a hydrogen halide or (c) with an alcohol or a thioalcohol in the presence of an alkali metal compound and/of an alkaline earth metal compound. The 2-aminopyrazines and pyrazines obtainable by the process of the invention are useful starting materials for the preparation of dyes, fungicides, bactericides, textile assistants, scents, folic acid derivatives, flavorings, and active ingredients in crop protection and drugs.