Coronary therapeutic agent in the form of soft gelatin capsules
US4689233A · kind A · utility
12Cited by
10References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 6, 1986 |
| Grant date | Aug 25, 1987 |
| Priority date | — |
| Expiry date | Jan 6, 2006 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/44
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a coronary therapeutic agent in the form of soft gelatin capsules, which contain the active substance nifedipine in an organic solvent. In the prior art, there where problems regarding the capsule size and with respect to the low nifedipine active substance concentration. These problems are obviated by the invention, in that nifedipine with PVP, optionally as a coprecipitate and without glycerin, is dissolved in THFP and consequently permits a capsule weight of in all only e.g. 162 mg.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.