Gamma-globulin preparation for intravenous administration
US4692331A · kind A · utility
13Cited by
5References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 24, 1984 |
| Grant date | Sep 8, 1987 |
| Priority date | — |
| Expiry date | Feb 24, 2004 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K39/39591
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A dry .gamma.-globulin preparation capable of intravenous injection which is obtainable by polyethylene glycol fractionation of plasma is improved in its water-solubility and stability against increase of anticomplement activity and decrease of antibody titer by purifying the .gamma.-globulin fraction with respect to protein to render the residual polyethylene glycol substantially not detectable in its 5% W/V solution, adding 0.2 to 2 parts by weight of glucose based on 1 part of .gamma.-globulin, and lyophilizing its solution.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.