6-substituted penem compounds
US4692442A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Nov 18, 1980 |
| Grant date | Sep 8, 1987 |
| Priority date | — |
| Expiry date | Nov 18, 2000 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/568
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to 2-penem-3-carboxylic acid compounds of the formula ##STR1## in which R.sub.a represents an organic radical bonded by a carbon atom to the ring carbon atom, a free, etherified or esterified hydroxy or mercapto group or a halogen atom, R.sub.1 represents hydrogen, an organic radical bonded by a carbon atom to the ring carbon atom, or an etherified mercapto group, and R.sub.2 represents a hydroxy group or an R.sub.2.sup.A radical that together with the carbonyl grouping --C(.dbd.O)-- forms a protected carboxyl group, and to salts of such compounds with salt-forming groups, processes for the manufacture of such compounds, pharmaceutical preparations containing compounds of the formula I with pharmacological properties, and their use. The compounds have antibiotic activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.