Liposomes containing steroid esters

US4693999A · kind A · utility

Assignee

• DRACO LTD. · SE

Inventors

• Bengt I. Axelsson · Genarp, SE
• Ralph Lennart Brattsand · Lund, SE
• Carl Magnus Olof Dahlback · Lund, SE
• Leif Arne Kallstrom · Södra Sandby, SE
• Jan Trofast · Lund, SE

Key dates

• Filing date: Jul 3, 1985
• Grant date: Sep 15, 1987
• Expiry date: Jul 3, 2005

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07J71/0031
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Pharmaceutical composition for administration primarily to the respiratory tract when treating and controlling anti-inflammatory conditions comprising liposomes in combination with a compound of the formula ##STR1## and R.sup.1 is a saturated or unsaturated, straight or branched alkyl group with 11-19 carbon atoms and R is H, --COCH.sub.3, --COC.sub.2 H.sub.5, --CO(CH.sub.2).sub.2 CH.sub.3 or --CO(CH.sub.2).sub.3 CH.sub.3. The invention also refers to the compounds of the formula I per se processes for preparation of these compounds and to a method for the treatment of inflammatory conditions.