Acyl- or acyloxymethyl-allopurinol prodrugs
US4694006A · kind A · utility
38Cited by
7References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 26, 1985 |
| Grant date | Sep 15, 1987 |
| Priority date | — |
| Expiry date | Feb 26, 2005 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds of the formula Ia and Ib ##STR1## are prodrugs of allopurinol and have i.a. a much higher solubility in water and/or a higher lipophilicity than allopurinol, which makes such compounds useful for oral, parenteral and rectal administration to a warm-blooded animal such as a human. Such compounds will after administration be converted into allopurinol.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.