Process for preparing compounds containing a difluoromethylene group in a position .alpha. to an oxygen atom
US4695657A · kind A · utility
1Cited by
2References
8Claims
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Inventor
Key dates
| Filing date | Dec 17, 1985 |
| Grant date | Sep 22, 1987 |
| Priority date | — |
| Expiry date | Dec 17, 2005 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C41/50
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process for the preparation of compounds containing a difluoromethylene group in a position .alpha. to an oxygen atom. An alcohol or a phenol is brought into contact with trifluoroacetic acid or a halide or anhydride thereof in anhydrous liquid hydrofluoric acid, in the presence of boron trifluoride, in a quantity such that the absolute pressure of boron trifluoride is at least about one bar. The compounds obtained according to the invention are used as synthesis intermediates in the pharmaceutical, plant-protection, and dye industries, as anesthetics and as additives for lubricating oils.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.