Certain 2-substituted 1,3-propylidenediphosphonate derivatives, pharmaceutical compositions containing them and their use as antihypertensive agents
US4696920A · kind A · utility
20Cited by
5References
29Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 16, 1985 |
| Grant date | Sep 29, 1987 |
| Priority date | — |
| Expiry date | Jul 16, 2005 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/6561
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
2-Substituted-1,3-propylidenediphosphonates of formula (I), where A, R.sup.1 and R.sup.2 are defined in claim 1, are therapeutically active compounds, namely for the treatment of cardiovascular diseases. They can be prepared by reacting phosphonating agents with 1,3- dibromopropanes or ditosylates of 1,3-propanediols substituted in position 2. ##STR1## .
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.