1-fluoro, 4-fluoro, and 1,4-difluoro anthracycline anticancer antibiotics
US4697005A · kind A · utility
10Cited by
2References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 20, 1985 |
| Grant date | Sep 29, 1987 |
| Priority date | — |
| Expiry date | Mar 20, 2005 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H15/252
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds represented by the formula (I) ##STR1## wherein R is hydrogen or hydroxyl, one of X and Y is fluorine and the other is hydrogen or both X and Y are fluorine, and Su is a hydrogen atom or a sugar moiety; where Su is a sugar moiety, the compounds are useful anticancer antibiotics; pharmaceutical preparations containing the antibiotics and a method for inhibiting the growth of mammalian tumors are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.